Physiological And Hormonal Effects of Bis Phenol S (BPS) on Etroplus Suratensis

Abstract- Concern has been raised in recent years that exposure to estrogenic chemicals can disrupt the endocrine functioning of fish and cause permanent alterations in the structure and function of the endocrine system. Plastic pollution in the aquatic environment has become a major problem in the freshwater and marine water system. Bisphenol S (BPS) has been frequently detected both in environment and biota, limited information is available on their effects of endocrine system. In the present study, Etroplus suratensis fishes were exposed to 50, 100, 150, 200 and 250 ppm of BPS for 28 d, and the effects on liver, antioxidant enzymes, MDA level and immunological parameters as Alkaline phosphatise, serum albumin, SGOT and SGPT were investigated. BPS leached from the discarded plastics, thermal papers directly affect the natural population of fishes in inland waters and as well as coastal waters. The experiment comprised of six groups of fishes including control. The LC 50 concentration of Bisphenol S exposed to Etroplus suratensis was found to be 407 ppm. The exposed fishes showed excess mucus secretion, abnormal movement, avoidance of feeds and high opercular movements. In all treatments after sub lethal exposure for 4 weeks the liver and blood collected for studies. The external changes of liver found as cyst formation in exposed group of fishes. The histopathological changes of liver included necrosis, vacuolation, congestion and rupture of hepatocytes. Specific activity of antioxidant enzymes GPx, SOD and CAT found to be decreased to the higher concentration of exposure level. Lipid peroxidation (LPO) was evaluated by means of malondialdehyde measurements (MDA). Exposure to BPS resulted in increased malondialdehyde (MDA) production. Serum albumin level is not effected by BPS but got slight decrease than the control. Serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT) and alkaline phosphatase (ALP) activity were elevated in exposed than the control.